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1

Pharmacological and Toxicological Effects of Catha edulis F. (Khat)

Engidawork, Ephrem

Journal:

Phytotherapy Research

Year:

2017

Language:

english

File:

PDF, 395 KB

english, 2017

2

Effects of Khat (Catha edulis) use on catalytic activities of major drug-metabolizing cytochrome P450 enzymes and implication of pharmacogenetic variations

Bedada, Worku, de Andrés, Fernando, Engidawork, Ephrem, Hussein, Jemal, LLerena, Adrián, Aklillu, Eleni

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

3

Major Depressive Disorder: Pathophysiology and Clinical Management.

Fekadu, Netsanet, Shibeshi, Workineh, Engidawork, Ephrem

Journal:

Journal of Depression & Anxiety

Year:

2017

Language:

english

File:

PDF, 462 KB

english, 2017

4

Prevalence of Cervical Cancer and Associated Risk Factors among Women Attending Cervical Cancer Screening and Diagnosis Center at Yirgalem General Hospital, Southern Ethiopia

Hailemariam, Tesfahun, Yohannes, Bizunesh, Aschenaki, Hiwot, Mamaye, Engidawork, Orkaido, Goye, Seta, Mihret

Journal:

Journal of Cancer Science & Therapy

Year:

2017

Language:

english

File:

PDF, 401 KB

english, 2017

5

Ethnobotanical Study of Medicinal Plants Used by Traditional Healers to Treat Cancer-Like Symptoms in Eleven Districts, Ethiopia

Tesfaye, Solomon, Belete, Anteneh, Engidawork, Ephrem, Gedif, Teferi, Asres, Kaleab

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2020

File:

PDF, 2.70 MB

2020

6

Evaluation of the Antipeptic Ulcer Activity of the Leaf Extract of Plantago lanceolata L. in Rodents

Endale Melese, Kaleab Asres, Mohammed Asad, Ephrem Engidawork

Journal:

Phytotherapy Research

Year:

2011

Language:

english

File:

PDF, 197 KB

english, 2011

7

Evaluation of the diuretic and analgesic activities of the rhizomes of Rumex abyssinicus Jacq in mice

Teshale Mekonnen, Kelbesa Urga, Ephrem Engidawork

Journal:

Journal of Ethnopharmacology

Year:

2010

Language:

english

File:

PDF, 208 KB

english, 2010

8

Renoprotective effects of the crude extract and solvent fractions of the leaves of Euclea divinorum Hierns against gentamicin-induced nephrotoxicity in rats

Feyissa, Tadiwos, Asres, Kaleab, Engidawork, Ephrem

Journal:

Journal of Ethnopharmacology

Year:

2013

Language:

english

File:

PDF, 900 KB

english, 2013

9

The Psychostimulant Khat (Catha edulis) Inhibits CYP2D6 Enzyme Activity in Humans

Bedada, Worku, de Andrés, Fernando, Engidawork, Ephrem, Pohanka, Anton, Beck, Olof, Bertilsson, Leif, Llerena, Adrián, Aklillu, Eleni

Journal:

Journal of Clinical Psychopharmacology

Year:

2015

Language:

english

File:

PDF, 224 KB

english, 2015

10

Analgesic and anti-inflammatory activities of 80% methanol root extract of Jasminum abyssinicum Hochst. ex. Dc. (Oleaceae) in mice

Tadiwos, Yohannes, Nedi, Teshome, Engidawork, Ephrem

Journal:

Journal of Ethnopharmacology

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

11

Levels of essential and toxic metals in Ethiopian khat, (Catha Edulis Forsk.)

Ashenef, A, Birhanu, G, Engidawork, E

Journal:

Ethiopian Journal of Environmental Studies and Management

Year:

2014

Language:

english

File:

PDF, 185 KB

english, 2014

12

Highly active antiretroviral therapy adherence and its determinants in selected hospitals from south and central Ethiopia

Kebede Abera Beyene, Teferi Gedif, Tsige Gebre-Mariam, Ephrem Engidawork

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2009

Language:

english

File:

PDF, 117 KB

english, 2009

13

Toxicity studies on dermal application of plant extract of Dodonaea viscosa used in Ethiopian traditional medicine

Kefale Teshome, Tsige Gebre-Mariam, Kaleab Asres, Ephrem Engidawork

Journal:

Phytotherapy Research

Year:

2010

Language:

english

File:

PDF, 181 KB

english, 2010

14

The neuropsychopharmacological effects of Catha edulis in mice offspring born to mothers exposed during pregnancy and lactation

Worku Bedada, Ephrem Engidawork

Journal:

Phytotherapy Research

Year:

2010

Language:

english

File:

PDF, 252 KB

english, 2010

15

Potential genotoxicity of plant extracts used in Ethiopian traditional medicine

J. Demma, E. Engidawork, B. Hellman

Journal:

Journal of Ethnopharmacology

Year:

2009

Language:

english

File:

PDF, 250 KB

english, 2009

16

Reproductive parameters are differentially altered following subchronic administration of Catha edulis F. (Khat) extract and cathinone in male rats

Abubeker Mohammed, Ephrem Engidawork

Journal:

Journal of Ethnopharmacology

Year:

2011

Language:

english

File:

PDF, 399 KB

english, 2011

17

Subchronic administration of Catha edulis F. (khat) extract is marked by elevation of cardiac biomarkers and subendocardial necrosis besides blood pressure alteration in rats

Endalkachew Admassie, Ephrem Engidawork

Journal:

Journal of Ethnopharmacology

Year:

2011

Language:

english

File:

PDF, 650 KB

english, 2011

18

In vivo wound healing activity and phytochemical screening of the crude extract and various fractions of Kalanchoe petitiana A. Rich (Crassulaceae) leaves in mice

Mekonnen, Awol, Sidamo, Temesgen, Asres, Kaleab, Engidawork, Ephrem

Journal:

Journal of Ethnopharmacology

Year:

2013

Language:

english

File:

PDF, 696 KB

english, 2013

19

Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians

Gebeyehu, E, Engidawork, E, Bijnsdorp, A, Aminy, A, Diczfalusy, U, Aklillu, E

Journal:

The Pharmacogenomics Journal

Year:

2011

Language:

english

File:

PDF, 379 KB

english, 2011

20

Fecal prevalence, serotype distribution and antimicrobial resistance of Salmonellae in dairy cattle in central Ethiopia

Eguale, Tadesse, Engidawork, Ephrem, Gebreyes, Wondwossen A., Asrat, Daniel, Alemayehu, Haile, Medhin, Girmay, Johnson, Roger P., Gunn, John S.

Journal:

BMC Microbiology

Year:

2016

Language:

english

File:

PDF, 719 KB

english, 2016

21

Perinatal Asphyxia Exerts Lifelong Effects on Neuronal Responsiveness to Stress in Specific Brain Regions in the Rat

hner, Peter Sale, Engidawork, Ephrem, Hoeger, Harald, Lubec, Barbara, Singewald, Nicolas

Journal:

Journal of Investigative Medicine

Year:

2003

File:

PDF, 30.56 MB

2003

22

Perinatal Asphyxia Exerts Lifelong Effects on Neuronal Responsiveness to Stress in Specific Brain Regions in the Rat

hner, Peter Sale, Engidawork, Ephrem, Hoeger, Harald, Lubec, Barbara, Singewald, Nicolas

Journal:

Journal of Investigative Medicine

Year:

2003

Language:

english

File:

PDF, 30.57 MB

english, 2003

23

Multiple challenges of antibiotic use in a large hospital in Ethiopia – a ward-specific study showing high rates of hospital-acquired infections and ineffective prophylaxis

Gutema, Girma, Håkonsen, Helle, Engidawork, Ephrem, Toverud, Else-Lydia

Journal:

BMC Health Services Research

Year:

2018

Language:

english

File:

PDF, 880 KB

english, 2018

24

Validation of the Amharic Version of the Brief Fatigue Inventory (BFI-Am) for Assessment of Cancer Related Fatigue in Ethiopian Cancer Patients

Gebremariam, Girma Tekle, Anshabo, Abel Tesfaye, Tigeneh, Wondemagegnhu, Engidawork, Ephrem

Journal:

Journal of Pain and Symptom Management

Year:

2018

Language:

english

File:

PDF, 998 KB

english, 2018

25

Methanolic Root Bark Extract and Solvent Fractions of Gardenia ternifolia Schumach. & Thonn. (Rubiaceae) against Plasmodium berghei

Nureye, Dejen, Assefa, Solomon, Nedi, Teshome, Engidawork, Ephrem

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

26

Antimalarial activity of the aqueous extract of the latex of Aloe pirottae Berger. (Aloaceae) against Plasmodium berghei in mice

Dibessa, Tesfa Tekle, Engidawork, Ephrem, Nedi, Teshome, Teklehaymanot, Tilahun

Journal:

Journal of Ethnopharmacology

Year:

2020

Language:

english

File:

PDF, 1.53 MB

english, 2020

27

Evaluation of the Antimalarial Activity of the Hydroalcoholic Extract of Leaf of Leonotis ocymifolia (Burm. f.) Iwarsson (Lamiaceae) against Plasmodium berghei in Mice

Teklu, Tewolde, Engidawork, Ephrem, Nedi, Teshome, Teklehaymanot, Tilahun, Gebremeskel, Leake

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2020

File:

PDF, 1.23 MB

2020

28

Differential expression of molecular chaperones in brain of patients with Down syndrome

Byong Chul Yoo, Roman Vlkolinsky, Ephrem Engidawork, Nigel Cairns, Michael Fountoulakis, Gert Lubec

Journal:

ELECTROPHORESIS

Year:

2001

Language:

english

File:

PDF, 219 KB

english, 2001

29

Molecular changes in fetal Down syndrome brain

Ephrem Engidawork, Gert Lubec

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 481 KB

english, 2003

30

Lead exposure study among workers in lead acid battery repair units of transport service enterprises, Addis Ababa, Ethiopia: a cross-sectional study

Kemal Ahmed, Gonfa Ayana, Ephrem Engidawork

Journal:

Journal of Occupational Medicine and Toxicology

Year:

2008

Language:

english

File:

PDF, 556 KB

english, 2008

31

Evaluation of in vivo antihypertensive and in vitro vasodepressor activities of the leaf extract of syzygium guineense (willd) D.C.

Yohannes Ayele, Kelbessa Urga, Ephrem Engidawork

Journal:

Phytotherapy Research

Year:

2010

Language:

english

File:

PDF, 318 KB

english, 2010

32

Delayed neuronal death following perinatal asphyxia in rat

Elisabetta Dell’Anna, Yong Chen, Ephrem Engidawork, Kurt Andersson, Gert Lubec, Johan Luthman, M. Herrera-Marschitz

Journal:

Experimental Brain Research

Year:

1997

Language:

english

File:

PDF, 1.18 MB

english, 1997

33

Long-term sequelae of perinatal asphyxia in the aging rat

R. Weitzdoerfer, N. Gerstl, H. Hoeger, W. Mosgoeller, W. Dreher, E. Engidawork, J. Overgaard-Larsen, B. Lubec

Journal:

Cellular and Molecular Life Sciences

Year:

2002

Language:

english

File:

PDF, 116 KB

english, 2002

34

Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia

E. Engidawork, F. Loidl, Y. Chen, C. Kohlhauser, S. Stoeckler, E. Dell'Anna, B. Lubec, G. Lubec, M. Goiny, J. Gross, K. Andersson, M. Herrera-Marschitz

Journal:

Experimental Brain Research

Year:

2001

Language:

english

File:

PDF, 67 KB

english, 2001

35

The brain in Down syndrome (TRISOMY 21)

Gert Lubec, Ephrem Engidawork

Journal:

Journal of Neurology

Year:

2002

Language:

english

File:

PDF, 7.74 MB

english, 2002

36

Identification and characterisation of soluble epoxide hydrolase in mouse brain by a robust protein biochemical method

J.-H. Shin, E. Engidawork, J.-M. Delabar, G. Lubec

Journal:

Year:

2005

Language:

english

File:

PDF, 563 KB

english, 2005

37

Manifold decrease of sialic acid synthase in fetal Down syndrome brain

T. Gulesserian, E. Engidawork, M. Fountoulakis, G. Lubec

Journal:

Year:

2007

Language:

english

File:

PDF, 73 KB

english, 2007

38

Long-term effect of moderate and profound hypothermia on morphology, neurological, cognitive and behavioural functions in a rat model of perinatal asphyxia

H. Hoeger, E. Engidawork, D. Stolzlechner, H. Bubna-Littitz, B. Lubec

Journal:

Year:

2006

Language:

english

File:

PDF, 301 KB

english, 2006

39

Protein expression in Down syndrome brain

E. Engidawork, G. Lubec

Journal:

Year:

2001

Language:

english

File:

PDF, 139 KB

english, 2001

40

Mass Spectrometrical Analysis of Galectin Proteins in Primary Rat Cerebellar Astrocytes

J. W. Yang, S. U. Kang, E. Engidawork, R. Rodrigo, V. Felipo, G. Lubec

Journal:

Neurochemical Research

Year:

2006

Language:

english

File:

PDF, 527 KB

english, 2006

41

An in vitro Study on the DNA Damaging Effects of Phytochemicals Partially Isolated from an Extract of Glinus Lotoides

Jemal Demma, Hesham El-Seedi, Ephrem Engidawork, Teshome Leta Aboye, Ulf Göransson, Björn Hellman

Journal:

Phytotherapy Research

Year:

2012

Language:

english

File:

PDF, 214 KB

english, 2012

42

Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders

Kurt Krapfenbauer, Ephrem Engidawork, Nigel Cairns, Michael Fountoulakis, Gert Lubec

Journal:

Year:

2003

Language:

english

File:

PDF, 547 KB

english, 2003

43

Short- and long-term effects of perinatal asphyxia on monoamine, amino acid and glycolysis product levels measured in the basal ganglia of the rat

Yong Chen, Ephrem Engidawork, Fabian Loidl, Elisabetta Dell'Anna, Michel Goiny, Gert Lubec, Kurt Andersson, Mario Herrera-Marschitz

Journal:

Developmental Brain Research

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

44

Alteration of Caspases and Apoptosis-Related Proteins in Brains of Patients with Alzheimer's Disease

Ephrem Engidawork, Talin Gulesserian, Byong Chul Yoo, Nigel Cairns, Gert Lubec

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 220 KB

english, 2001

45

Effect of Perinatal Asphyxia on Systemic and Intracerebral pH and Glycolysis Metabolism in the Rat

Ephrem Engidawork, Yong Chen, Elisabetta Dell'Anna, Michel Goiny, Gert Lubec, Urban Ungerstedt, Kurt Andersson, Mario Herrera-Marschitz

Journal:

Experimental Neurology

Year:

1997

Language:

english

File:

PDF, 231 KB

english, 1997

46

Toxicological study on Glinus lotoides: A traditionally used taenicidal herb in Ethiopia

Jemal Demma, Tsige Gebre-Mariam, Kaleab Asres, Wondwossen Ergetie, Ephrem Engidawork

Journal:

Journal of Ethnopharmacology

Year:

2007

Language:

english

File:

PDF, 153 KB

english, 2007

47

Toxicity studies on dermal application of plant extract of Plumbago zeylanica used in Ethiopian traditional medicine

Kefale Teshome, Tsige Gebre-Mariam, Kaleab Asres, Franklin Perry, Ephrem Engidawork

Journal:

Journal of Ethnopharmacology

Year:

2008

Language:

english

File:

PDF, 476 KB

english, 2008

48

Neuronal nitric oxide synthase knock-out mice show impaired cognitive performance

Rachel Weitzdoerfer, Harald Hoeger, Efrem Engidawork, Mario Engelmann, Nicolas Singewald, Gert Lubec, Barbara Lubec

Journal:

Year:

2004

Language:

english

File:

PDF, 218 KB

english, 2004

49

Increased protein levels of serotonin transporter in frontal cortex of patients with Down syndrome

Talin Gulesserian, Ephrem Engidawork, Nigel Cairns, Gert Lubec

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 141 KB

english, 2000

50

Expression of apoptosis related proteins in brains of patients with Alzheimer's disease

Ephrem Engidawork, Talin Gulesserian, Rainer Seidl, Nigel Cairns, Gert Lubec

Journal:

Neuroscience Letters

Year:

2001

Language:

english

File:

PDF, 85 KB

english, 2001